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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-320
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples and adjacent noncancerous tissues; RB cell line WERI-RB1
Methods qRT-PCR, siRNA transfection, Western blot, luciferase reporter assay
Expression pattern up-regulated
Functional description miRNA-320 may regulate the development of autophagy by targeting HIF-1α and autophagy-related proteins in RB under hypoxic conditions.
PubMed ID 28962169
Year 2017
Title MicroRNA-320 regulates autophagy in retinoblastoma by targeting hypoxia inducible factor-1α.
Drug-related ncRNA NO

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